Simone is Clouseau's wife and a main antagonist in the first film. She is a supporting character in "Trail of the Pink Panther" and "Curse of the Pink Panther". She is played by Capucine. Simone is introduced as Clouseau's wife in the first film, but is secretly the lover and partner-in-crime of Sir Charles Lytton, The Phantom, the world's greatest catburglar. Thanks to her intervention, Clouseau can never catch him. She accompanies Clouseau to the ski resort where Princess Dala, owner of the world's greatest diamond, The Pink Panther, is staying, as Clouseau knows that The Phantom will try to steal it. Simone and Lytton continue their affair, while she is also pursued by Lytton's nephew, George Lytton. Clouseau remains devoted to his wife, unaware of the fact that she is constantly deceiving him. After Lytton and his nephew have been arrested as suspects, Simone teams up with Dala to frame Clouseau and free them. She is shown to feel remorse after Clouseau is arrested, but she never gets back together with him.
In "Trail of the Pink Panther", Simone and Lytton are shown to be married, and are interviewed by Marie who is interviewing most of the characters who knew Clouseau.
All three Lyttons appear in "Curse of the Pink Panther" on their yacht, helping the hero, Clifton Sleigh, on his search for Clouseau and the diamond. At the end of the film they steal the diamond from Clouseau.